Inhibition of pathogen adhesion to host cells by polysaccharides from Panax ginseng.

نویسندگان

  • Ji-Hye Lee
  • Jin Sun Shim
  • Mi-Sook Chung
  • Seung-Taik Lim
  • Kyung Hyun Kim
چکیده

PG-F2 and PG-HMW from Panax ginseng are pectin-type polysaccharides and PG-HMW might be an arabinogalactan. They demonstrated strong anti-adhesive activities against oral and skin pathogens to host cell lines in a dose-dependent manner from 0.1 to 2.0 mg/ml. While enzymatic hydrolysis caused complete loss of anti-adhesive activities, partial hydrolysis produced oligosaccharides with anti-adhesive properties. PG-F2 and PG-HMW might have a selective anti-adhesive effect against certain pathogenic bacteria without adverse effects on commensal bacteria.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 73 1  شماره 

صفحات  -

تاریخ انتشار 2009